Spray
Use once per nostril as directed.
A Modern Way to Treat ED
Rapid Results, Instant Chemistry
ROXUS reimagines a proven class of ED therapy using advanced intranasal delivery.
By working with the body’s own vascular pathways, ROXUS is designed for rapid absorption and reliable effect with a lower systemic dose.
What is ROXUS?
Ask AI
ROXUS is a compounded vardenafil nasal spray for erectile dysfunction (ED), available only by prescription.
Disclaimer: AI responses may contain inaccuracies and are not medical advice.
How it Works
From desire to action in minutes*Three simple steps from spray to confidence.
Contains a clinically proven PDE5 inhibitor via nasal delivery.
Reference:
*Data on file, 2026
How fast does ROXUS work?
Ask AI
ROXUS is designed to begin working in minutes, versus roughly 30 to 60 minutes for ED tablets.
Disclaimer: AI responses may contain inaccuracies and are not medical advice.
The nose knows
Why intranasal delivery matters
Rapid onset, convenience, consistency, and flexibility make intranasal delivery an advanced alternative for ED therapy.
ROXUS® works in minutes*
Oral tablets work in 30-120 minutes
Onset Time
Delivery Route
Dosage Efficiency
Convenience
Consistency
Experience
Onset Time
Works in minutes
Delivery Route
Direct absorption through nasal membrane
Dosage Efficiency
Lower systemic dose required
Convenience
Discreet, on-the-go use
Consistency
More predictable absorption and results
Experience
Fast, modern, on-demand
Onset Time
Takes 30–120 minutes to take effect
Delivery Route
Digestive system and liver metabolism
Dosage Efficiency
Higher dose needed for same effect
Convenience
Must be planned ahead of time
Consistency
Variable absorption due to food or metabolism
Experience
Slower, less flexible experience
What is a nasal spray for erectile dysfunction?
Ask AI
An ED nasal spray, like ROXUS, delivers a PDE5 inhibitor through the nasal lining instead of a swallowed tablet or pill.
Disclaimer: AI responses may contain inaccuracies and are not medical advice.
For patients
Intimacy on-demand
ED affects millions of men. Roxus provides a new option that can help restore intimacy and confidence.
0
%
of men 40-70+ are affected by erectile dysfunction
0
15
%
of relationship breakdowns have identified ED as a major factor
References:
Feldman, H.A., Goldstein, I., Hatzichristou, D.G., Krane, R.J., & McKinlay, J.B. (1994). “Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study.” The Journal of Urology, 151(1), 54–61.
Nimbi, F.M., et al. (2021). “Is Female Wellness Affected When Men Blame Them for Erectile Dysfunction?” Sexual Medicine / PMC8240332.
Real Stories
I’ve never been a fan of tablets, so having a nasal spray option just makes more sense for me. It feels straightforward and easy to use.”
— Kyle, 22
Customer from U.S.
It just feels more immediate for my lifestyle.”
— Nick, 38
Customer from U.S.
The nasal spray fits easily into my routine. I like that it’s simple, fast, and doesn’t interrupt the moment.”
— Tim, 67
Customer from U.S.
I feel less stressed knowing I have something that fits naturally into the moment. It takes some pressure off.
— Steven, 45
Customer from U.S.
I’ve never been a fan of tablets, so having a nasal spray option just makes more sense for me. It feels straightforward and easy to use.”
— Justyn, 42
Customer from U.S.
It just feels more immediate for my lifestyle.”
— Chris, 38
Customer from U.S.
It just feels more immediate for my lifestyle.”
— Chris, 38
Customer from U.S.
I feel less stressed knowing I have something that fits naturally into the moment. It takes some pressure off.
— Stuart, 42
Customer from U.S.
Backed by science
Improvement on established treatment
ROXUS builds on established PDE5 science with intranasal absorption that allows efficient therapeutic effect.
Nasal administration improves absorption, optimized bioavailability, and a streamlined dose-to-response relationship.
ROXUS is a compounded medication. Compounded drugs are not FDA-approved and are not reviewed for safety, effectiveness, or quality. They are prepared for a specific patient based on a valid prescription.
A new standard in ED care
ROXUS represents a rethinking of spontaneous, effective ED therapy.
Fast.
Discreet.
Proven Class.
Modern Delivery.
For clinicians
A Modern route for proven therapy
ROXUS offers a modern route for PDE5 therapy with the potential to improve adherence and satisfaction.
Proven mechanism, efficient uptake, and targeted delivery make it an appealing option.
Backed by leading health experts
ROXUS partners with experienced clinicians and advisors to deliver high‑quality care at scale. Their guidance helps shape modern ED treatment pathways and patient‑first delivery.
Professor Eric Chung
Professor of Surgery (Urology)
Professor Eric Chung is a leading Australian urological surgeon and a professor at The University of Queensland. He is an expert in male sexual, reproductive, and urinary health, with subspecialty interests including urinary dysfunction, erectile restoration, and reconstructive/prosthetic surgery. He is recognized for his pioneering work as the first urologist in Australia to complete an accredited Andrology fellowship in North America and holds numerous executive positions in international medical organizations
University of Queensland
Dr. Amy Pearlman
Board-Certified Urologist
Dr Amy Pearlman is Co-founder of Prime Institute in Coral Gables, Florida, a premium private medical practice specialising in cardiometabolic, hormonal, and sexual health optimisation. She is a fellowship-trained specialist in male sexual and hormonal health and former Director of the Men’s Health Program at the University of Iowa. Dr Pearlman serves on the editorial board for Urology Times, is a board member of the Sexual Medicine Society of North America (SMSNA) and is an active member of the American Urological Association (AUA). She was a key contributor to the Fifth International Consultation on Sexual Medicine (ICSM 2024), helping to shape global policy and recommendations in sexual health.
Fellowship: Wake Forest University
Dr. Andrew Sun
Board-Certified Urologist
Dr Andrew Sun is Director of Men’s Health at Urology Partners of North Texas, one of the state’s largest men’s health clinics. He completed his medical training at Harvard Medical School, residency at the Cleveland Clinic Glickman Urological and Kidney Institute, and fellowship training in Male Reproductive Medicine and Surgery at UCLA. Dr Sun contributes to clinical guidelines for the Sexual Medicine Society of North America (SMSNA) and leads national training programs in erectile restoration with Boston Scientific. He is an active member of the American Urological Association (AUA), American Society for Reproductive Medicine (ASRM), and International Society for Sexual Medicine (ISSM).
Harvard Medical School
Melissa Hadley Barrett (NP)
Urology Nurse Practitioner and Sexologist
Melissa Hadley Barrett is the founder of Restorative Health Clinic and one of Australia’s longest-practicing Nurse Practitioners. With postgraduate qualifications in Sexology and extensive experience in men’s sexual health, she helps individuals and couples improve sexual function, intimacy and overall wellbeing. Her approach combines medical expertise with a strong understanding of the psychological side of sexual health, delivering care that is both evidence-based and compassionate. Melissa has supported thousands of men through prostate cancer recovery and other sexual health challenges, and is widely recognized as a speaker, educator and reviewer of international sexual health guidelines.
Curtin University
Join Our Patient Community.
"*" indicates required fields
The more you know.
Frequently asked questions
What is ROXUS?
ROXUS is a nasal spray erectile dysfunction treatment designed for rapid onset.
What makes it unique?
Unlike oral medications that undergo liver metabolism (first-pass), intranasal delivery bypasses this step, leading to a more immediate and potent drug effect
Why Nasal delivery?
The nasal mucosa is highly vascular, ensuring rapid and efficient drug absorption
How long does it take to work?
By bypassing the digestive system, ROXUS works within minutes.
What is the recommended daily dose of Roxus?
The recommended daily dose is 5mg administered through 2 fully dispensed sprays, (1 spray into each nostril).
Keeping your data safe
Your medical information is stored on Roxus’s HIPAA-compliant.
Need answers now?
Email info@roxus.com
Safety Information: Do not use Roxus with nitrates or guanylate cyclase stimulators. Seek immediate help for erections lasting over four hours. Stop use and contact your doctor for sudden vision or hearing loss. Always follow medical guidance.
Join our community.
"*" indicates required fields